Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962262 | 0.95 | PSMB5 (0.54) | PSMB5GAARAB9AUSP30GRIA1 | |
| SCHEMBL12004867 | 0.91 | GRIA1 (0.56) | PSMB5GAARAB9AUSP30GRIA1 | |
| SCHEMBL3938112 | 0.91 | GRIA1 (0.56) | PSMB5GAARAB9AUSP30GRIA1 | |
| SCHEMBL8013304 | 0.89 | PSMB5 (0.59) | PSMB5L3MBTL1ITGB1ITGA5ITGB3 | |
| SCHEMBL21623659 | 0.86 | PSMB5 (0.62) | PSMB5L3MBTL1USP30GPR132 | |
| SCHEMBL9554481 | 0.86 | PSMB5 (0.62) | PSMB5L3MBTL1USP30GPR132 | |
| SCHEMBL9554659 | 0.84 | GRIA1 (0.61) | PSMB5ITGB1ITGA5USP30GPR132 | |
| SCHEMBL25496515 | 0.84 | PSMB5 (0.60) | PSMB5L3MBTL1GAARAB9AUSP30 | |
| SCHEMBL31389155 | 0.84 | PSMB5 (0.60) | PSMB5L3MBTL1GAARAB9AUSP30 | |
| SCHEMBL28495150 | 0.84 | SMN1; SMN2 (0.52) | PSMB5L3MBTL1GAARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197793-B1 | VIRICIDES, BACTERICIDES, FUNGICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-03-06 | — | — | US | claimed |
| EP-0861029-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-02-17 | — | — | EP | claimed |
| EP-0861029-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997017850-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | claimed |
| US-6197793-B1 | VIRICIDES, BACTERICIDES, FUNGICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-03-06 | — | — | US | disclosed |
| EP-0861029-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-02-17 | — | — | EP | disclosed |
| EP-0861029-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017850-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |