Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554481 | 0.97 | PSMB5 (0.62) | PSMB5PTPN1GPR132USP30L3MBTL1 | |
| SCHEMBL21623659 | 0.97 | PSMB5 (0.62) | PSMB5PTPN1GPR132USP30L3MBTL1 | |
| SCHEMBL9554659 | 0.95 | GRIA1 (0.61) | PSMB5ITGB1ITGA5GRIA1PTPN1 | |
| SCHEMBL12015221 | 0.90 | PSMB5 (0.51) | PSMB5ITGB1ITGA5GRIA1PTPN1 | |
| SCHEMBL7959534 | 0.89 | PSMB5 (0.53) | PSMB5ITGB1ITGA5GRIA1GPR132 | |
| SCHEMBL19899634 | 0.88 | FPR2 (0.56) | PSMB5ITGB1ITGA5PTPN1GPR132 | |
| SCHEMBL19899636 | 0.88 | FPR2 (0.56) | PSMB5ITGB1ITGA5PTPN1GPR132 | |
| SCHEMBL23633254 | 0.86 | GRM4 (0.53) | PSMB5ITGB1ITGA5GPR132L3MBTL1 | |
| SCHEMBL19899396 | 0.86 | GRM4 (0.53) | PSMB5ITGB1ITGA5GPR132L3MBTL1 | |
| SCHEMBL19899394 | 0.86 | GRM4 (0.53) | PSMB5ITGB1ITGA5GPR132L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030989-A | Hemoregulatory compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| US-6030989-A | Hemoregulatory compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0861078-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0861078-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017965-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |