Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938112 | 0.95 | GRIA1 (0.56) | PSMB5GRIA1RAB9AGAANPC1 | |
| SCHEMBL7959534 | 0.95 | PSMB5 (0.53) | PSMB5GRIA1RAB9AGAAUSP30 | |
| SCHEMBL12004867 | 0.95 | GRIA1 (0.56) | PSMB5GRIA1RAB9AGAANPC1 | |
| SCHEMBL28495150 | 0.88 | SMN1; SMN2 (0.52) | PSMB5RAB9AGAANPC1PKM | |
| SCHEMBL12984674 | 0.87 | SMN1; SMN2 (0.51) | PSMB5RAB9AGAANPC1PKM | |
| SCHEMBL25496515 | 0.86 | PSMB5 (0.60) | PSMB5RAB9AGAANPC1PKM | |
| SCHEMBL31389155 | 0.86 | PSMB5 (0.60) | PSMB5RAB9AGAANPC1PKM | |
| SCHEMBL12984057 | 0.85 | TP53 (0.51) | PSMB5RAB9AGAANPC1PKM | |
| SCHEMBL4990568 | 0.82 | SMN1; SMN2 (0.55) | RAB9AGAANPC1PKMKDM4E | |
| SCHEMBL8013304 | 0.82 | PSMB5 (0.59) | PSMB5GRIA1USP30CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197793-B1 | VIRICIDES, BACTERICIDES, FUNGICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6030989-A | Hemoregulatory compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0861078-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0861029-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-02-17 | — | — | EP | disclosed |
| EP-0861029-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0861078-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017850-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |
| WO-1997017965-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |