SCHEMBL7959754

SCHEMBL7959754

[CH2]OCc1cc(OC)c(OC)c(OC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.59
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
HTR2B P41595 1/20 0.53
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
TUBB1 Q9H4B7 4/20 0.50
TUBB4A P04350 3/20 0.50
TUBB P07437 3/20 0.50
TUBA3C P0DPH7 3/20 0.50
TUBA1B P68363 3/20 0.50
TUBA4A P68366 3/20 0.50
TUBB4B P68371 3/20 0.50
TUBB3 Q13509 3/20 0.50
TUBB2A Q13885 3/20 0.50
TUBB8 Q3ZCM7 3/20 0.50
TUBA3E Q6PEY2 3/20 0.50
TUBA1A Q71U36 3/20 0.50
TUBA1C Q9BQE3 3/20 0.50
TUBB6 Q9BUF5 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959757 0.82 PTGS2 (0.64) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL7961363 0.82 PTGS2 (0.64) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL7956528 0.79 PTGS2 (0.55) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL11841088 0.78 PTGS2 (0.59) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL1714741 0.78 PTGS2 (0.59) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL27464444 0.78 PTGS2 (0.53) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL900800 0.77 PTGS2 (0.64) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL31432799 0.77 PTGS2 (0.63) PTGS2HTR2AHTR2CHTR2BCYP3A4
Hydrochloric Acid SCHEMBL1715075 0.77 PTGS2 (0.57) PTGS2HTR2AHTR2CHTR2BCYP3A4
SCHEMBL291362 0.77 CA2 (0.63) CYP3A4MAPTABCB1CYP19A1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245779-B1 ANALGESICS; ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2001-06-12 US disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 EP disclosed