Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GPR65 | Q8IYL9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796111 | 0.87 | HCRTR1 (0.34) | L3MBTL1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL795998 | 0.83 | HCRTR1 (0.32) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL796498 | 0.82 | GRM5 (0.38) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL795931 | 0.77 | TDP1 (0.36) | L3MBTL1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL795549 | 0.76 | HDAC6 (0.41) | ADORA2AADORA3ADORA1ADORA2BNPC1 | |
| SCHEMBL795809 | 0.76 | MAPT (0.36) | L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL797207 | 0.75 | KMT2A (0.34) | L3MBTL1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL795733 | 0.75 | GRM5 (0.35) | ADORA2AKDM4EALDH1A1ADORA1HCRTR2 | |
| SCHEMBL797183 | 0.75 | ALOX5AP (0.44) | ADORA2AALDH1A1ADORA3ADORA1NR1H4 | |
| SCHEMBL808341 | 0.75 | PTGIR (0.34) | KDM4EALDH1A1HPGDHSD17B10HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025057-A1 | Triazine-oxadiazoles | NOVARTIS AG (CH) | 2015-01-22 | — | — | US | disclosed |
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025057-A1 | Triazine-oxadiazoles | OPRK1, OPRD1, OPRL1 | L3MBTL1 4747/4885ADORA2A 244/4885KDM4E 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.