Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.44 |
| ▸ | SPPL2A | Q8TCT8 | 2/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959974 | 1.00 | RORC (0.44) | RORCSPPL2ATAS2R14MEN1KMT2A | |
| SCHEMBL2576474 | 1.00 | RORC (0.44) | RORCSPPL2ATAS2R14MEN1KMT2A | |
| SCHEMBL2578910 | 0.93 | TAS2R14 (0.47) | RORCSPPL2ATAS2R14MEN1KMT2A | |
| SCHEMBL2582931 | 0.93 | TAS2R14 (0.47) | RORCSPPL2ATAS2R14MEN1KMT2A | |
| SCHEMBL2581281 | 0.91 | TAS2R14 (0.51) | TAS2R14BACE1 | |
| SCHEMBL2582413 | 0.91 | SPPL2A (0.52) | RORCSPPL2ATAS2R14 | |
| SCHEMBL2578860 | 0.90 | MAPK1 (0.47) | RORCSPPL2AMEN1KMT2AMAPT | |
| SCHEMBL2587456 | 0.90 | CA12 (0.48) | RORCTAS2R14MEN1KMT2ABACE1 | |
| SCHEMBL2578820 | 0.89 | RXFP1 (0.45) | RORCTAS2R14MEN1KMT2ABACE1 | |
| SCHEMBL2578314 | 0.89 | MEN1 (0.42) | RORCSPPL2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169085-B1 | A VIRICIDE FOR PREVENTING AND TREATING RETROVIRAL INFECTION OR THE SPREAD OF A RETROVIRUS, INHIBITING REPLICATION OF A RETROVIRUS AND TREATING AIDS | G. D. SEARLE & COMPANY | 2001-01-02 | — | — | US | disclosed |