Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320232 | 0.98 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL31683702 | 0.98 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL30531662 | 0.98 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4836149 | 0.95 | LMNA (0.47) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Lactic Acid SCHEMBL28460211 | 0.91 | TP53 (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Hexadecane SCHEMBL28029400 | 0.86 | KDM4E (0.67) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL3635596 | 0.84 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4729415 | 0.84 | KDM4E (0.42) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Butyric Acid SCHEMBL27902376 | 0.83 | KDM4E (0.50) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Citric Acid SCHEMBL30003489 | 0.80 | ALDH1A1 (0.48) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6260699-B1 | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-5468252-A | Filled suture | UNITED STATES SURGICAL CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| US-5462162-A | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0471441-B1 | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORP (US) | 1995-09-27 | — | — | EP | disclosed |
| US-5366081-A | Packaged synthetic absorbable surgical elements | UNITED STATES SURGICAL CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5222978-A | Sutures filled with stabilizer | UNITED STATES SURGICAL CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0471441-A1 | Packaged synthetic absorbable surgical elements | United States Surgical Corporation (US) | 1992-02-19 | — | — | EP | disclosed |
| US-5081150-A | Drugs, cosmetics, foods | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |