Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973031 | 0.85 | HDAC3 (0.64) | ALDH1A1HTTPKMNPY5RLMNA | |
| SCHEMBL7973349 | 0.84 | NPY5R (0.63) | ALDH1A1HTTPKMKMT2ANPY5R | |
| SCHEMBL2139445 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTPKMKMT2AMAPT | |
| SCHEMBL2139442 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTPKMKMT2AMAPT | |
| SCHEMBL7960267 | 0.74 | HDAC3 (0.73) | KMT2ANPY5RPOLBMEN1 | |
| SCHEMBL29877086 | 0.74 | HDAC3 (0.73) | KMT2ANPY5RPOLBMEN1 | |
| SCHEMBL7971400 | 0.74 | NPY5R (0.72) | ALDH1A1KMT2ANPY5RPOLBMEN1 | |
| SCHEMBL441272 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL441271 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL12572060 | 0.71 | KMT2A (0.72) | ALDH1A1HTTPKMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |