Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971400 | 0.89 | NPY5R (0.72) | NPY5RALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7973031 | 0.89 | HDAC3 (0.64) | NPY5RALDH1A1PKMHTT | |
| SCHEMBL7960188 | 0.84 | ALDH1A1 (0.56) | NPY5RALDH1A1PKMMEN1KMT2A | |
| SCHEMBL3851599 | 0.82 | NPY5R (0.68) | NPY5RALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2139442 | 0.82 | ALDH1A1 (0.53) | NPY5RALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2139445 | 0.82 | ALDH1A1 (0.53) | NPY5RALDH1A1PKMMEN1KMT2A | |
| SCHEMBL7960267 | 0.78 | HDAC3 (0.73) | NPY5RMEN1KMT2APOLB | |
| SCHEMBL7960086 | 0.76 | NPY5R (0.56) | NPY5RALDH1A1POLB | |
| SCHEMBL3851236 | 0.75 | GBA1 (0.79) | NPY5RALDH1A1PKMMEN1KMT2A | |
| SCHEMBL5205575 | 0.75 | GBA1 (0.79) | NPY5RALDH1A1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |