Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056761 | 0.90 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL7206486 | 0.89 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CCREBBP | |
| SCHEMBL7958772 | 0.89 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CCREBBP | |
| SCHEMBL7206484 | 0.89 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CCREBBP | |
| SCHEMBL2044860 | 0.85 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL7211003 | 0.84 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL7211005 | 0.84 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| Hydrochloric Acid SCHEMBL8387939 | 0.84 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8387934 | 0.84 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CL3MBTL1 | |
| SCHEMBL2882721 | 0.81 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191138-B1 | THERAPY FOR RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-02-20 | — | — | US | disclosed |