Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319448 | 0.84 | PDE4A (0.52) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6583750 | 0.82 | PDE4A (0.58) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8574011 | 0.78 | PDE4A (0.52) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL11428703 | 0.78 | PDE4A (0.54) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8590946 | 0.75 | PDE4A (0.51) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7322576 | 0.74 | PDE4A (0.55) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7325901 | 0.73 | PDE4A (0.54) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7042502 | 0.73 | PDE4A (0.76) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6585871 | 0.72 | PDE4A (0.61) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8483975 | 0.72 | PDE4A (0.66) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |