Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960558 | 0.84 | PDE4A (0.46) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5567417 | 0.81 | PDE4A (0.67) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7042502 | 0.79 | PDE4A (0.76) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5610531 | 0.78 | PDE4A (0.59) | PDE4APDE4BPDE4DPDE4C | |
| Hydrochloric Acid SCHEMBL7907751 | 0.78 | PDE4D (0.76) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7317788 | 0.77 | PDE4A (0.53) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7908614 | 0.77 | PDE4A (0.51) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7175088 | 0.76 | PDE4A (0.65) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7357576 | 0.75 | PDE4A (0.72) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL13799356 | 0.75 | PDE4A (0.61) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580888-A | Styryl derivatives as anti-inflammatory agents | CELLTECH THERAPEUTICS LIMITED (GB) | 1996-12-03 | — | — | US | disclosed |
| EP-0626957-A1 | STYRIL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994014800-A1 | STYRIL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |