Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 4/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10173105 | 0.84 | HTR1A (0.41) | HTR1ATNIKF10FASNRHEB | |
| SCHEMBL7977838 | 0.82 | F10 (0.39) | TNIKF10F9F11F7 | |
| SCHEMBL7959321 | 0.80 | F10 (0.40) | TNIKF10F9F11F7 | |
| SCHEMBL20307796 | 0.79 | F9 (0.44) | F10F9F11F7RHEB | |
| SCHEMBL10172741 | 0.72 | F9 (0.53) | F10F9F11F7RHEB | |
| SCHEMBL7969419 | 0.71 | F9 (0.52) | F10F9F11F7RHEB | |
| SCHEMBL7978212 | 0.71 | F9 (0.65) | F10F9F11F7FASN | |
| SCHEMBL19994743 | 0.69 | RHEB (0.51) | FASNRHEB | |
| SCHEMBL30343735 | 0.69 | RHEB (0.51) | FASNRHEB | |
| SCHEMBL10140918 | 0.69 | F10 (0.37) | TNIKF10GRK6CDK2CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |