Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959321 | 0.96 | F10 (0.40) | F10F9F11F7TNIK | |
| SCHEMBL7966289 | 0.84 | F10 (0.39) | F10TNIKGRK6BRD4GSK3B | |
| SCHEMBL7970800 | 0.83 | TNKS (0.43) | F10F9F11F7CDK2 | |
| SCHEMBL10140047 | 0.83 | F10 (0.40) | F10TNIKGRK6GSK3BCCNC | |
| SCHEMBL7960559 | 0.82 | HTR1A (0.41) | F10F9F11F7TNIK | |
| SCHEMBL7975114 | 0.80 | F9 (0.42) | F10F9F11F7CDK2 | |
| SCHEMBL10140048 | 0.80 | F10 (0.38) | F10TNIKGRK6CCNCCDK8 | |
| SCHEMBL7975730 | 0.79 | F10 (0.37) | F10TNIKGRK6GSK3BCCNC | |
| SCHEMBL16258933 | 0.78 | F9 (0.47) | F10F9F11F7ALDH1A1 | |
| SCHEMBL7975112 | 0.78 | F9 (0.47) | F10F9F11F7BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |