Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | F9 | P00740 | 3/20 | 0.37 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258969 | 0.86 | F10 (0.35) | F10F7F2F9F11 | |
| SCHEMBL10140002 | 0.84 | F10 (0.49) | F10F7F2F9F11 | |
| SCHEMBL10140128 | 0.84 | F10 (0.34) | F10F7F2F9F11 | |
| SCHEMBL10140114 | 0.77 | F10 (0.47) | F10F7F2F9F11 | |
| SCHEMBL16258916 | 0.77 | NOS3 (0.34) | NOS3NOS1HDAC1HDAC6ADCY10 | |
| SCHEMBL7971691 | 0.76 | CHEK2 (0.40) | F10F7F2F9F11 | |
| SCHEMBL10139992 | 0.76 | CHEK2 (0.50) | — | |
| SCHEMBL7977546 | 0.75 | F10 (0.68) | F10F7F2F9F11 | |
| SCHEMBL10140129 | 0.75 | HDAC1 (0.34) | NOS3NOS1HDAC1HDAC6KLKB1 | |
| SCHEMBL10139884 | 0.73 | F10 (0.48) | F10F7F2F9F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |