Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960654 | 1.00 | KLK7 (0.36) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7963204 | 0.89 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7279530 | 0.83 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7270193 | 0.83 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7279540 | 0.83 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7270189 | 0.83 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL5833363 | 0.83 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL7962411 | 0.83 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL2175304 | 0.83 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ABCB1 | |
| SCHEMBL2175307 | 0.83 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |