Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 7/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960654 | 0.89 | KLK7 (0.36) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7960653 | 0.89 | KLK7 (0.36) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7279530 | 0.87 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7270193 | 0.87 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7279540 | 0.87 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7270189 | 0.87 | KLK7 (0.38) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL5833363 | 0.86 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL7962411 | 0.86 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL2175307 | 0.86 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ALDH1A1 | |
| SCHEMBL2175304 | 0.86 | KLK7 (0.40) | KLK7KLK5GPR119MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |