Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.57 |
| ▸ | TACR1 | P25103 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956966 | 0.85 | NPY1R (0.74) | NPY1R | |
| SCHEMBL7958711 | 0.84 | NPY1R (0.66) | NPY1R | |
| SCHEMBL7958847 | 0.82 | NPY1R (0.74) | NPY1R | |
| SCHEMBL7956724 | 0.82 | NPY1R (0.75) | NPY1RKMT2A | |
| SCHEMBL7959736 | 0.80 | NPY1R (0.51) | NPY1R | |
| SCHEMBL7959732 | 0.80 | NPY1R (0.51) | NPY1R | |
| SCHEMBL7960734 | 0.80 | NPY1R (0.65) | NPY1RALDH1A1HPGD | |
| SCHEMBL7956831 | 0.79 | NPY1R (0.75) | NPY1RMEN1KMT2A | |
| SCHEMBL7959769 | 0.78 | NPY1R (0.62) | NPY1RALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7963655 | 0.77 | NPY1R (0.60) | NPY1RLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |