Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21882 | 0.96 | — | — | |
| SCHEMBL6689804 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL1406213 | 0.92 | CES2 (0.46) | TSHRLMNACES1CES2THRB | |
| SCHEMBL11525884 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL4849581 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL11531992 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| Iodide SCHEMBL7869089 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL11527395 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL747847 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB | |
| SCHEMBL10591515 | 0.92 | TSHR (0.43) | TSHRLMNACES1CES2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100374411-C | Process for preparing racemic or optically active 4- (hydroxymethyl) -2-cyclopentene derivatives | LONZA CO LTD (CH) | 2008-03-12 | — | — | CN | disclosed |
| CN-1302116-C | Process for preparing enantiomers of (1R, 4S) -or (1S, 4R) -1-amino-4- (hydroxymethyl) -2-cyclopentene derivatives | LONZE AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| CN-1827591-A | Process for preparing racemic or optically active 4- (hydroxymethyl) -2-cyclopentene derivatives | LONZA AG (CH) | 2006-09-06 | — | — | CN | disclosed |
| CN-1515673-A | Process for preparing enantiomers of (1R, 4S) -or (1S, 4R) -1-amino-4- (hydroxymethyl) -2-cyclopentene derivatives | ��¡���ӹɷ�����˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1115343-C | Process for the preparation of (1S,4R) -or (1R,4S) -4- (2-amino-6-chloro-9H-purin-9-yl) -2-cyclopentene-1-methanol or salts thereof | LONZA AG (CH) | 2003-07-23 | — | — | CN | disclosed |
| US-6262295-B1 | REACTING CYCLOPENTENE-4-CARBOXYLIC ACID WITH AN ACYL HALIDE | LONZA A.G. (CH) | 2001-07-17 | — | — | US | disclosed |
| US-6252112-B1 | MIBCROBIAL HYDROLYSIS OF THE TITLE COMPOUND DERIVATIVE USING ENZYME HAVING N-ACETYLAMINO-ALCOHOL HYDROLASE OR PENICILLIN G ACYLASE ACTIVITY WITH SUBSEQUENT ACYLATION | LONZA A.G., (CH) | 2001-06-26 | — | — | US | disclosed |
| US-6156893-A | Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol | LONZA A.G. (CH) | 2000-12-05 | — | — | US | disclosed |
| US-6137007-A | CHEMICAL INTERMEDIATES FOR NUCLEOSIDE, 4-2-(AMINO-6-CHLORO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL, WHICH IS AN INTERMEDIATE FOR 6-(CYCLOPROPYLAMINO)-DERIVATIVE | LONZA AG (CH) | 2000-10-24 | — | — | US | disclosed |
| CN-1201794-A | Process for the preparation of (1S,4R) -or (1R,4S) -4- (2-amino-6-chloro-9H-purin-9-yl) -2-cyclopentene-1-methanol or salts thereof | LONZA AG (CH) | 1998-12-16 | — | — | CN | disclosed |