Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178809 | 0.92 | CCKBR (0.52) | CCKBR | |
| SCHEMBL6193739 | 0.91 | CCKBR (0.42) | CCKBRKMT2ALMNA | |
| SCHEMBL6177998 | 0.89 | CCKBR (0.47) | CCKBRKMT2ALMNA | |
| SCHEMBL6179079 | 0.88 | CCKBR (0.49) | CCKBRKMT2A | |
| SCHEMBL6178953 | 0.86 | CCKBR (0.47) | CCKBRKMT2ALMNA | |
| SCHEMBL6180301 | 0.86 | CCKBR (0.47) | CCKBRKMT2ALMNA | |
| SCHEMBL6181818 | 0.85 | CCKBR (0.50) | CCKBRKMT2ALMNA | |
| SCHEMBL6181169 | 0.82 | CCKBR (0.48) | CCKBRKMT2A | |
| SCHEMBL7960830 | 0.82 | CCKBR (0.35) | CCKBRLMNA | |
| SCHEMBL6177012 | 0.82 | CCKBR (0.49) | CCKBRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |