Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962064 | 0.85 | CCKBR (0.36) | CCKBRLMNASCN9ATSHR | |
| SCHEMBL6176603 | 0.84 | CCKBR (0.39) | CCKBRLMNASCN9ATSHR | |
| SCHEMBL6209886 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL7959681 | 0.83 | CCKBR (0.35) | CCKBRSCN9A | |
| SCHEMBL6181983 | 0.82 | CCKBR (0.36) | CCKBRLMNASCN9A | |
| SCHEMBL6178809 | 0.82 | CCKBR (0.52) | CCKBR | |
| SCHEMBL7960957 | 0.82 | CCKBR (0.47) | CCKBRLMNA | |
| SCHEMBL6176827 | 0.79 | SCN9A (0.43) | CCKBRSCN9A | |
| SCHEMBL7960425 | 0.78 | ALDH1A1 (0.40) | CCKBRLMNASCN9ATSHR | |
| SCHEMBL6178660 | 0.77 | CCKBR (0.38) | CCKBRLMNASCN9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |