Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 9/20 | 0.47 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7951516 | 0.98 | MMP3 (0.56) | MMP3SMN1; SMN2MMP9MMP2MAPK1 | |
| SCHEMBL7955836 | 0.87 | MMP2 (0.52) | SMN1; SMN2MMP9MMP2MMP1MMP14 | |
| SCHEMBL1381157 | 0.86 | MMP3 (0.53) | MMP3SMN1; SMN2MMP9MMP2ALDH1A1 | |
| Hydroxyamine SCHEMBL1378161 | 0.84 | MMP3 (0.51) | MMP3SMN1; SMN2MMP9MMP2ALDH1A1 | |
| SCHEMBL6418945 | 0.84 | MMP3 (0.62) | MMP3MMP9MMP2MMP1MMP14 | |
| SCHEMBL6421326 | 0.82 | MMP3 (0.64) | MMP3MMP9MMP2MMP14MMP13 | |
| SCHEMBL6421316 | 0.82 | MMP3 (0.64) | MMP3MMP9MMP2MMP14MMP13 | |
| SCHEMBL4431389 | 0.81 | MMP3 (0.70) | MMP3MMP9MMP2MMP1ALDH1A1 | |
| SCHEMBL6419780 | 0.81 | MMP3 (0.67) | MMP3MMP9MMP2MMP1ALDH1A1 | |
| SCHEMBL4431378 | 0.81 | MMP3 (0.70) | MMP3MMP9MMP2MMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277987-B1 | FOR INHIBITING MATRIX-DEGRADING METALLOPROTEINASES IN MAMMALS | NOVARTIS AG (CH) | 2001-08-21 | — | — | US | disclosed |