Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.70 |
| ▸ | AR | P10275 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955312 | 0.91 | PGR (0.77) | PGRNR3C1AR | |
| SCHEMBL5889099 | 0.88 | PGR (1.00) | PGRNR3C1AR | |
| SCHEMBL5889167 | 0.84 | PGR (0.77) | PGRNR3C1AR | |
| SCHEMBL7946226 | 0.83 | PGR (0.84) | PGRNR3C1AR | |
| SCHEMBL6648084 | 0.80 | PGR (0.78) | PGRNR3C1AR | |
| SCHEMBL6648906 | 0.78 | PGR (0.72) | PGRNR3C1AR | |
| SCHEMBL7953137 | 0.78 | PGR (0.75) | PGRNR3C1AR | |
| SCHEMBL12899044 | 0.77 | PGR (0.87) | PGRNR3C1AR | |
| SCHEMBL7953145 | 0.77 | PGR (0.68) | PGRNR3C1AR | |
| SCHEMBL7954577 | 0.77 | PGR (1.00) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268497-B1 | CONVERTING LACTOL PRECURSOR TO ONE OF A SELECT NUMBER OF MIXED ACETAL DERIVATIVES, AND THEN TREATING ACETALS WITH A GRIGNARD REAGENT TO PROVIDE CHROMENOQUINOLINE COMPOUND | LIGAND PHARMACEUTICALS INCORPORATED | 2001-07-31 | — | — | US | disclosed |