Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961980 | 1.00 | PDE4A (0.53) | PDE4AKCNH2P2RX7ALDH1A1GAA | |
| SCHEMBL7960495 | 0.88 | PDE4A (0.54) | PDE4AKCNH2P2RX7PDE4BPDE4C | |
| SCHEMBL7953933 | 0.87 | PDE4A (0.53) | PDE4AKCNH2P2RX7PDE4BPDE4C | |
| SCHEMBL7961918 | 0.86 | PDE4A (0.58) | PDE4AKCNH2PDE4BPDE4CPDE4D | |
| SCHEMBL7961917 | 0.86 | PDE4A (0.58) | PDE4AKCNH2PDE4BPDE4CPDE4D | |
| SCHEMBL7963864 | 0.86 | ALDH1A1 (0.48) | PDE4AKCNH2ALDH1A1GAAPDE4B | |
| SCHEMBL7954789 | 0.86 | ALDH1A1 (0.48) | PDE4AKCNH2ALDH1A1GAAPDE4B | |
| SCHEMBL7960506 | 0.85 | PDE4A (0.66) | PDE4AKCNH2PDE4BPDE4CPDE4D | |
| SCHEMBL7953478 | 0.85 | PDE4A (0.53) | PDE4AKCNH2P2RX7PDE4BPDE4C | |
| SCHEMBL7953479 | 0.85 | PDE4A (0.53) | PDE4AKCNH2P2RX7PDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0978516-A1 | 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SUNTORY LIMITED (JP) | 2000-02-09 | — | — | EP | disclosed |