Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962254 | 0.91 | MAPT (0.40) | MAPTLMNAPTGS2ALDH1A1MAOB | |
| SCHEMBL7962256 | 0.91 | MAPT (0.40) | MAPTLMNAPTGS2ALDH1A1MAOB | |
| SCHEMBL7957578 | 0.88 | MAPT (0.39) | MAPTLMNAPTGS2ALDH1A1POLB | |
| SCHEMBL7948100 | 0.88 | NT5E (0.55) | MAPTLMNAALDH1A1NT5E | |
| SCHEMBL8313564 | 0.86 | CYP1A2 (0.43) | ALDH1A1MAOB | |
| SCHEMBL7962085 | 0.86 | CYP1A2 (0.43) | ALDH1A1MAOB | |
| SCHEMBL7955497 | 0.82 | NT5E (0.41) | MAPTLMNAALDH1A1NT5EKDM4E | |
| SCHEMBL7955494 | 0.82 | NT5E (0.41) | MAPTLMNAALDH1A1NT5EKDM4E | |
| SCHEMBL8319213 | 0.81 | CYP1A2 (0.39) | MAPTALDH1A1KCNH2NT5E | |
| SCHEMBL7957573 | 0.81 | CYP1A2 (0.39) | MAPTALDH1A1KCNH2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |