Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959250 | 0.78 | TP53 (0.53) | UNGTP53MAPTLMNAHPGD | |
| SCHEMBL2416578 | 0.75 | LMNA (0.50) | UNGTP53MAPTLMNAHSD17B10 | |
| SCHEMBL1266331 | 0.71 | STK17A (0.54) | UNGTP53LMNAHSD17B10THRA | |
| SCHEMBL1264648 | 0.71 | STK17A (0.54) | UNGTP53LMNAHSD17B10THRA | |
| SCHEMBL9330419 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL | |
| SCHEMBL9502209 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL | |
| SCHEMBL284616 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL | |
| SCHEMBL11699858 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL | |
| SCHEMBL9330410 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL | |
| SCHEMBL2391508 | 0.71 | ESR1 (0.61) | UNGTP53LMNAHSD17B10MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177437-B1 | VIRICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER | 2001-01-23 | — | — | US | disclosed |