Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 15/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 15/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 14/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7960652 | 0.99 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BOPRM1CHRM4 | |
| SCHEMBL7964723 | 0.84 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7968128 | 0.84 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7964726 | 0.84 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7963344 | 0.84 | ADRA1A (0.63) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7964640 | 0.80 | ADRA1A (0.66) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7955656 | 0.80 | ADRA1A (0.66) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7955653 | 0.80 | ADRA1A (0.66) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| Hydrochloric Acid SCHEMBL7967320 | 0.80 | ADRA1A (0.65) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7963932 | 0.78 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BCHRM4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | claimed |
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | disclosed |