Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20674534 | 0.77 | PTPN2 (0.44) | BAZ2BBAZ2APTPN2PTPN1ALDH1A1 | |
| SCHEMBL25970044 | 0.75 | PTPN2 (0.37) | USP7RAD51BAZ2BBAZ2APTPN2 | |
| SCHEMBL20674632 | 0.71 | USP7 (0.41) | USP7BAZ2BBAZ2APTPN2PTPN1 | |
| SCHEMBL25970052 | 0.71 | MAT2A (0.41) | USP7RAD51BAZ2BBAZ2AALDH1A1 | |
| SCHEMBL20674636 | 0.70 | SSTR4 (0.36) | BAZ2BBAZ2APTPN2PTPN1ALDH1A1 | |
| SCHEMBL20674622 | 0.70 | TDP1 (0.46) | USP7PTPN2PTPN1ALDH1A1GAA | |
| SCHEMBL20674621 | 0.70 | BAZ2B (0.46) | BAZ2BBAZ2AALDH1A1KDM4EGAA | |
| SCHEMBL20674634 | 0.69 | KDM4E (0.41) | BAZ2BBAZ2AALDH1A1KDM4EGAA | |
| SCHEMBL20674631 | 0.69 | BAZ2B (0.41) | BAZ2BBAZ2APTPN2PTPN1ALDH1A1 | |
| SCHEMBL24734786 | 0.68 | PTPN1 (0.61) | RAD51PTPN2PTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |