Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.61 |
| ▸ | RAD51 | Q06609 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375291 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL13169648 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL31531848 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL31377558 | 0.76 | PTPN1 (0.61) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL8569855 | 0.76 | PTPN1 (0.61) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL20816342 | 0.75 | RAD51 (0.78) | PTPN1PTPN2RAD51MEN1KMT2A | |
| SCHEMBL1312896 | 0.74 | CSNK2A2 (0.55) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL20674534 | 0.73 | PTPN2 (0.44) | PTPN1PTPN2KDM4EALDH1A1HPGD | |
| SCHEMBL20836377 | 0.73 | RAD51 (0.78) | PTPN1PTPN2RAD51KDM4EALDH1A1 | |
| SCHEMBL13345880 | 0.73 | PTPN1 (0.57) | PTPN1PTPN2RAD51KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | HSPA9, ATF4, GPX4 | PTPN1 4635/4885PTPN2 4541/4885RAD51 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.