Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | CDC25A | P30304 | 6/20 | 0.70 |
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | NSD2 | O96028 | 6/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.70 |
| ▸ | MITF | O75030 | 4/20 | 0.70 |
| ▸ | APAF1 | O14727 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CDC25B | P30305 | 3/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277646 | 0.95 | MAPT (0.72) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL15906861 | 0.89 | MAPT (0.75) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL8631267 | 0.89 | ALDH1A1 (0.58) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL1101039 | 0.83 | MAPT (0.46) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL17249965 | 0.82 | MAPT (1.00) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL7964190 | 0.81 | APAF1 (0.51) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL11266802 | 0.80 | MAPT (0.51) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL9326036 | 0.80 | NSD2 (0.83) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL12283411 | 0.79 | CDC25A (0.71) | MAPTCDC25AHTTLMNANSD2 | |
| SCHEMBL7829354 | 0.79 | CDC25A (1.00) | MAPTCDC25AHTTLMNANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654321-A | ANTICOAGULANTS | DONG KOOK PHARMACEUTICAL CO. LTD. (KR) | 1997-08-05 | — | — | US | claimed |
| JP-9208551-A | — | — | None | — | — | JP | disclosed |
| US-6174918-B1 | INHIBITING TUMOR CELL GROWTH SENSITIVE TO NAPHTHOQUINONE DERIVATIVE IN MAMMAL BY ADMINISTERING 2,3-DISUBSTITUTED NAPHTHOQUINONE COMPOUND | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2001-01-16 | — | — | US | disclosed |
| US-5789431-A | INHIBITING CELL TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1997030022-A1 | NAPHTHOQUINONE ANTITUMOR COMPOUND AND METHOD | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-08-21 | — | — | WO | disclosed |
| JP-H09208551-A | NEW 2-CHLORO-3-ARYLAMINO-1,4-NAPHTHOQUINONE, ITS PRODUCTION AND ITS USE AS BLOOD PLATELET COAGULATION INHIBITOR | DONG KOOK PHARMACEUT CO | 1997-08-12 | — | — | JP | disclosed |
| US-5654321-A | ANTICOAGULANTS | DONG KOOK PHARMACEUTICAL CO. LTD. (KR) | 1997-08-05 | — | — | US | disclosed |
| US-5654321-A | ANTICOAGULANTS | DONG KOOK PHARMACEUTICAL CO. LTD. (KR) | 1997-08-05 | — | — | US | disclosed |
| US-5654321-A | ANTICOAGULANTS | DONG KOOK PHARMACEUTICAL CO. LTD. (KR) | 1997-08-05 | — | — | US | disclosed |