Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FGF1 | P05230 | 2/20 | 0.33 |
| ▸ | FGF2 | P09038 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962356 | 0.91 | NT5E (0.48) | NT5EHTTNPC1RAB9ASSTR5 | |
| SCHEMBL8316593 | 0.91 | NT5E (0.48) | NT5EHTTNPC1RAB9ASSTR5 | |
| SCHEMBL7957682 | 0.90 | NT5E (0.54) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7957675 | 0.86 | NT5E (0.50) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7957983 | 0.86 | NT5E (0.52) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7957672 | 0.86 | NT5E (0.50) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7957980 | 0.86 | NT5E (0.52) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7955443 | 0.83 | NT5E (0.50) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7955444 | 0.83 | NT5E (0.50) | NT5EHTTNPC1RAB9ASSTR1 | |
| SCHEMBL7957678 | 0.83 | NT5E (0.52) | NT5EHTTNPC1RAB9ASSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |