Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973304 | 0.95 | AMY1A (0.34) | KCNH2AMY1ATOP1TOP2AGUSB | |
| SCHEMBL7970587 | 0.93 | TOP1 (0.34) | KCNH2SSTR2AMY1AF9F10 | |
| SCHEMBL7970061 | 0.91 | GUSB (0.39) | PDE10AAMY1ATOP1TOP2AGUSB | |
| SCHEMBL7973155 | 0.89 | F9 (0.39) | F9F10F11TOP1TOP2A | |
| SCHEMBL7960212 | 0.89 | AMY1A (0.35) | KCNH2SSTR2AMY1AF9F10 | |
| SCHEMBL7971418 | 0.89 | SCD (0.42) | PDE10AAMY1AGUSB | |
| SCHEMBL7970581 | 0.88 | F9 (0.40) | F9F10F11TOP1TOP2A | |
| SCHEMBL7962296 | 0.87 | NPBWR1 (0.36) | GUSBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7972135 | 0.86 | PDE10A (0.37) | KCNH2PDE10AF9F10F11 | |
| SCHEMBL10139972 | 0.85 | AMY1A (0.37) | AMY1ATOP1TOP2AGUSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |