Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | SNCA | P37840 | 3/20 | 0.47 |
| ▸ | DHPS | P49366 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616920 | 0.82 | HTR6 (0.60) | SRCAPPSNCAHTR2CHTR6 | |
| SCHEMBL7809472 | 0.76 | KMT2A (0.60) | APPSNCACYP11B1HTR6CHRNB2 | |
| SCHEMBL7736703 | 0.75 | EGLN1 (0.59) | APPHTR2CHTR6KDM4ELMNA | |
| SCHEMBL22547192 | 0.74 | HTR2C (0.49) | APPSNCAHTR2CHTR6 | |
| SCHEMBL22547180 | 0.72 | HTR2C (0.48) | APPSNCAHTR2CHTR6 | |
| SCHEMBL22533784 | 0.72 | HTR2C (0.48) | APPSNCAHTR2CHTR6 | |
| SCHEMBL17127823 | 0.72 | GRIN2B (0.50) | SRCDHPSCNR1CNR2CYP11B1 | |
| SCHEMBL17372069 | 0.71 | HTR2C (0.62) | APPSNCAHTR2CCNR1CNR2 | |
| SCHEMBL4321418 | 0.71 | HTR2C (0.60) | APPSNCAHTR2CHTR6KDM4E | |
| SCHEMBL22533614 | 0.70 | HTR2C (0.46) | APPSNCAHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074803-A1 | METHOD FOR PREPARING 3-(4-HYDROXY-1H-INDOL-YLMETHYL)-PYRIDINIUM COMPOUNDS USING AN ALDOLISATION REACTION | L'OREAL (FR) | 2001-10-11 | — | — | WO | disclosed |