Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DBH | P09172 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616920 | 0.86 | HTR6 (0.60) | HTR6ALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL28477449 | 0.79 | HTR6 (0.55) | EGLN1HTR6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22547192 | 0.78 | HTR2C (0.49) | EGLN1HTR6HTR2CAPP | |
| SCHEMBL30218818 | 0.77 | HTR6 (0.59) | EGLN1HTR6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6085311 | 0.77 | HTR6 (0.59) | EGLN1HTR6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22533784 | 0.77 | HTR2C (0.48) | EGLN1HTR6HTR2CAPP | |
| SCHEMBL22547180 | 0.77 | HTR2C (0.48) | EGLN1HTR6HTR2CAPP | |
| SCHEMBL7962478 | 0.75 | SRC (0.52) | HTR6KDM4EHTTLMNAHTR2C | |
| SCHEMBL6824243 | 0.75 | PLAU (0.54) | EGLN1HTR6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1770473 | 0.75 | EGLN1 (1.00) | EGLN1ALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407261-B1 | OXIDIZING THE CORRESPONDING KETONE COMPOUND BY HEATING WITH A SUKFINATING COMPOUND | ELI LILLY AND COMPANY | 2002-06-18 | — | — | US | disclosed |