Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972452 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BITGAVTPSAB1 | |
| SCHEMBL7962515 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BHTTLMNATSHR | |
| SCHEMBL7086294 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BKMT2ANAMPT | |
| SCHEMBL7086286 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BKMT2ANAMPT | |
| SCHEMBL7962531 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BLMNAGAAALDH1A1 | |
| SCHEMBL6984596 | 0.80 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL9394430 | 0.80 | ITGB3 (0.57) | ITGB3ITGA2BKMT2AGAA | |
| SCHEMBL7387014 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BKMT2ANAMPT | |
| SCHEMBL7387179 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BKMT2ANAMPT | |
| SCHEMBL9394717 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BKMT2AITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | claimed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | claimed |
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | disclosed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | disclosed |