Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.54 |
| ▸ | F2 | P00734 | 6/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086294 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9559140 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7085479 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2BCYP3A4 | |
| SCHEMBL6975938 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2BCYP3A4 | |
| SCHEMBL9558494 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6984596 | 0.84 | ITGB3 (0.76) | ITGB3ITGA2BF2 | |
| SCHEMBL7962529 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BNAMPTKMT2A | |
| SCHEMBL9394430 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7962531 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BF2 | |
| SCHEMBL9558989 | 0.82 | F2 (0.51) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |