Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187469 | 0.87 | OPRM1 (0.55) | OPRM1OPRD1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL315411 | 0.85 | OPRM1 (0.53) | OPRM1OPRD1CA12CA1CA2 | |
| Water SCHEMBL8580355 | 0.84 | OPRM1 (0.52) | OPRM1OPRD1CA12CA1CA2 | |
| Propionic Acid SCHEMBL6476615 | 0.84 | OPRM1 (0.49) | OPRM1OPRD1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL14343612 | 0.77 | OPRD1 (0.46) | OPRM1OPRD1CA12CA1CA2 | |
| Methyl Isobutyl Ketone SCHEMBL8583311 | 0.75 | OPRD1 (0.45) | OPRM1OPRD1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL30369525 | 0.75 | MEN1 (0.43) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL432561 | 0.74 | OPRM1 (0.59) | OPRM1OPRD1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8846380 | 0.74 | AKR1C1 (0.50) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL6198658 | 0.71 | OPRM1 (0.47) | OPRM1OPRD1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | disclosed |