Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953297 | 0.89 | LMNA (0.55) | ABCB1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7969773 | 0.85 | ABCB1 (0.47) | ABCB1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7962733 | 0.85 | ABCB1 (0.39) | ABCB1 | |
| SCHEMBL7953490 | 0.85 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL7962723 | 0.84 | MAP4K4 (0.36) | ABCB1MEN1KMT2A | |
| SCHEMBL7966028 | 0.83 | ABCB1 (0.54) | ABCB1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7953682 | 0.83 | ABCB1 (0.47) | ABCB1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7964373 | 0.83 | ABCB1 (0.63) | ABCB1 | |
| SCHEMBL7953962 | 0.82 | ABCB1 (0.54) | ABCB1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8019951 | 0.82 | MEN1 (0.49) | ABCB1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |