Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953297 | 0.89 | LMNA (0.55) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7965198 | 0.88 | PRMT5 (0.45) | ABCB1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7968936 | 0.86 | ABCB1 (0.52) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7962728 | 0.85 | ABCB1 (0.54) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7969776 | 0.85 | OPRL1 (0.35) | ABCB1 | |
| SCHEMBL8132545 | 0.84 | NOTUM (0.33) | MAPT | |
| SCHEMBL7966028 | 0.84 | ABCB1 (0.54) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7953682 | 0.83 | ABCB1 (0.47) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7965342 | 0.83 | KMT2A (0.44) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7953962 | 0.83 | ABCB1 (0.54) | ABCB1LMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |