Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.50 |
| ▸ | NQO2 | P16083 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013960 | 0.88 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2ABCB11SIGMAR1 | |
| SCHEMBL6076698 | 0.87 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2ABCB11SIGMAR1 | |
| SCHEMBL7022012 | 0.85 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7021058 | 0.80 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL6077298 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BNQO2ABCB11SIGMAR1 | |
| SCHEMBL5346153 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL6076702 | 0.77 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6077044 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL7021486 | 0.76 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8794011 | 0.76 | KDM4C (0.41) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |