Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.57 |
| ▸ | NQO2 | P16083 | 15/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021486 | 0.90 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5223857 | 0.88 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL7021058 | 0.86 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL7963135 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7198659 | 0.84 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5225817 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5227713 | 0.81 | HTR1A (0.59) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5223865 | 0.79 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5479142 | 0.79 | HTR1A (0.54) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL5226600 | 0.78 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |