Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 12/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958633 | 0.88 | TBXA2R (0.40) | PTGIRTBXA2RPTGDR2P2RX3TP53 | |
| SCHEMBL7956568 | 0.86 | GLA (0.35) | PTGIRTBXA2R | |
| SCHEMBL7959858 | 0.85 | TBXA2R (0.37) | PTGIRTBXA2RPTGDR2P2RX3TP53 | |
| SCHEMBL7963138 | 0.80 | TBXA2R (0.56) | PTGIRTBXA2RPTGDR2P2RX3TP53 | |
| SCHEMBL7948671 | 0.80 | PTGIR (0.34) | PTGIRTBXA2RPTGDR2P2RX3TP53 | |
| SCHEMBL7959853 | 0.71 | TBXA2R (0.40) | PTGIRTBXA2RPTGDR2P2RX3TP53 | |
| SCHEMBL7958632 | 0.71 | TBXA2R (0.44) | PTGIRTBXA2RPTGDR2P2RX3 | |
| SCHEMBL7948667 | 0.66 | TBXA2R (0.37) | PTGIRTBXA2RPTGDR2P2RX3 | |
| SCHEMBL7956157 | 0.66 | TBXA2R (0.58) | PTGIRTBXA2RPOLBKDM4EALDH1A1 | |
| SCHEMBL7956565 | 0.66 | MEN1 (0.39) | PTGIRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |