Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963142 | 0.86 | PTGIR (0.48) | TBXA2RPTGIR | |
| SCHEMBL7956565 | 0.80 | MEN1 (0.39) | GLASTING1TBXA2RPTGIRMEN1 | |
| SCHEMBL7958633 | 0.74 | TBXA2R (0.40) | TBXA2RPTGIR | |
| SCHEMBL7959858 | 0.71 | TBXA2R (0.37) | TBXA2RPTGIR | |
| SCHEMBL7963138 | 0.66 | TBXA2R (0.56) | TBXA2RPTGIRMEN1KMT2A | |
| SCHEMBL7948790 | 0.64 | SMN1; SMN2 (0.41) | TBXA2RPTGIRMEN1KMT2A | |
| SCHEMBL7221504 | 0.64 | HPGD (0.44) | MEN1KMT2A | |
| SCHEMBL13686149 | 0.63 | SLC6A3 (0.46) | PTGER4MEN1KMT2ASLC6A3 | |
| SCHEMBL5003478 | 0.63 | MEN1 (0.39) | MEN1KMT2ASLC6A3 | |
| SCHEMBL11770475 | 0.61 | ITGB1 (0.40) | MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |