Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192815 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBMAPTTSHR | |
| SCHEMBL7965133 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBMAPTTSHR | |
| SCHEMBL10595738 | 0.74 | HSD17B10 (0.48) | ALDH1A1KDM4EPOLBMAPTTSHR | |
| SCHEMBL4264381 | 0.70 | CRBN (0.39) | CRBNTLR4NPSR1 | |
| SCHEMBL13242146 | 0.69 | CRBN (0.37) | CRBN | |
| SCHEMBL10534278 | 0.68 | TLR4 (0.64) | ALDH1A1KDM4EPOLBTLR4ALOX15 | |
| SCHEMBL14441739 | 0.67 | TLR4 (0.36) | TLR4NPSR1 | |
| SCHEMBL10591889 | 0.65 | ALDH1A1 (0.35) | ALDH1A1MAPTCRBNTLR4 | |
| SCHEMBL18998460 | 0.64 | — | — | |
| SCHEMBL15032678 | 0.64 | MAPK1 (0.44) | TLR4MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |