SCHEMBL7963305

SCHEMBL7963305

CS(=O)(=O)OCC1CC[N]CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MMP9 P14780 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14414058 0.84 USP2 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1062380 0.84
SCHEMBL7705221 0.84 USP2 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1710717 0.80 LMNA (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL121125 0.80 LMNA (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4317153 0.80 KDM4E (0.41) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2206227 0.78 LMNA (0.37) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL20491528 0.78 LMNA (0.37) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1710596 0.78 LMNA (0.37) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2208804 0.78 LMNA (0.37) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed