Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293526 | 0.80 | TAS1R3 (0.53) | DPP7DPP8DPP9DPP4SLC15A1 | |
| SCHEMBL6547737 | 0.79 | PLA2G2C (0.62) | PLA2G2CDPP7DPP8DPP9DPP4 | |
| SCHEMBL292770 | 0.77 | TAS1R3 (0.45) | CA2CA1TAS1R3TAS1R1 | |
| SCHEMBL4856257 | 0.76 | PLA2G2C (0.56) | PLA2G2CDPP7CA2MAPK1 | |
| SCHEMBL11506429 | 0.76 | PLA2G2C (0.59) | PLA2G2CDPP7DPP8DPP9DPP4 | |
| SCHEMBL20914941 | 0.76 | PLA2G2C (0.51) | PLA2G2CDPP7DPP8DPP9DPP4 | |
| SCHEMBL292566 | 0.75 | — | — | |
| SCHEMBL2666554 | 0.74 | PLA2G2C (0.67) | PLA2G2CCA2 | |
| SCHEMBL1258599 | 0.74 | PLA2G2C (0.64) | PLA2G2CCA2MAPK1 | |
| SCHEMBL28751562 | 0.74 | PLA2G2C (0.67) | PLA2G2CCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |