Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499685 | 1.00 | ALOX5 (0.38) | ALOX5SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7966868 | 1.00 | ALOX5 (0.38) | ALOX5SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7970569 | 0.80 | BCL2 (0.33) | — | |
| SCHEMBL7964901 | 0.80 | BCL2 (0.33) | — | |
| SCHEMBL7964237 | 0.79 | AKR1B1 (0.38) | SMN1; SMN2RAB9AMAPTALDH1A1ABCC9 | |
| SCHEMBL7952174 | 0.79 | AKR1B1 (0.38) | SMN1; SMN2RAB9AMAPTALDH1A1ABCC9 | |
| SCHEMBL7964272 | 0.79 | AKR1B1 (0.38) | SMN1; SMN2RAB9AMAPTALDH1A1ABCC9 | |
| SCHEMBL6983916 | 0.79 | AKR1B1 (0.38) | SMN1; SMN2RAB9AMAPTALDH1A1ABCC9 | |
| SCHEMBL7963402 | 0.79 | AKR1B1 (0.38) | SMN1; SMN2RAB9AMAPTALDH1A1ABCC9 | |
| SCHEMBL7964893 | 0.77 | KDM4E (0.44) | KDM4EABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |