Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 2/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756228 | 0.87 | MAPT (0.42) | OPRM1TXNRD1GSRKMT2ATDP1 | |
| SCHEMBL5755781 | 0.81 | KMT2A (0.37) | OPRM1KDM4EKMT2A | |
| SCHEMBL5754892 | 0.76 | OPRM1 (0.40) | OPRM1KDM4EGUSBEBPSIGMAR1 | |
| SCHEMBL5758740 | 0.72 | KDM1A (0.42) | OPRM1SIGMAR1 | |
| SCHEMBL5751667 | 0.72 | OPRM1 (0.46) | OPRM1KDM4E | |
| SCHEMBL5752933 | 0.72 | DRD3 (0.57) | OPRM1 | |
| SCHEMBL5754428 | 0.72 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL5753482 | 0.70 | ALDH1A1 (0.40) | KDM4ETDP1SIGMAR1 | |
| SCHEMBL5755049 | 0.70 | NPSR1 (0.41) | OPRM1SIGMAR1 | |
| SCHEMBL5755872 | 0.70 | ALDH1A1 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313312-B1 | OPIATE RECEPTOR BINDERS; ALLERGIC DERMATITIS, PRURITUS; IRRITABLE BOWEL SYNDROME, GASTROINTESTINAL AND SKIN DISORDERS; VETERINARY MEDICINE; ANTI-ITCHING | PFIZER INC | 2001-11-06 | — | — | US | disclosed |