Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963513 | 0.91 | MAPT (0.83) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7977321 | 0.84 | NPY5R (1.00) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7973739 | 0.84 | REV1 (0.84) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7963462 | 0.83 | NPY5R (1.00) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4727570 | 0.83 | NPY5R (1.00) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7977372 | 0.82 | REV1 (0.81) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7722815 | 0.79 | NPSR1 (1.00) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7979360 | 0.79 | REV1 (0.69) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7977012 | 0.78 | REV1 (0.68) | NPY5RMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14199692 | 0.78 | MAPT (0.82) | NPY5RMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |