Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 16/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974783 | 0.88 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7963464 | 0.84 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7963462 | 0.83 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29434775 | 0.79 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6826732 | 0.79 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL1594119 | 0.79 | NPY5R (0.72) | NPY5RKDM4ENPC1MEN1MAPT | |
| SCHEMBL6829168 | 0.78 | NPY5R (1.00) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7963513 | 0.77 | MAPT (0.83) | NPY5RKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL1593465 | 0.75 | NPY5R (1.00) | NPY5RKDM4EMEN1MAPTKMT2A | |
| SCHEMBL178526 | 0.74 | NPC1 (0.71) | NPY5RKDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |